Kev tshawb fawb | Cov nyhuv tshuaj pleev ib ce raw khoom - arbutin Tshooj Ob

Lub tshuab ntxuav hniav dawb ntawm arbutin

Cov ntsiab lus thiab kev faib tawm ntawmmelanin  yog lub ntsiab tseem ceeb uas txiav txim siab qhov tob ntawm daim tawv nqaij xim. Melanin yog tsim nyob rau hauv melanocytes nyob rau hauv lub basal txheej ntawm daim tawv nqaij epidermis. Nws yog thaum kawg tsim los ntawm tyrosine nyob rau hauv qhov kev txiav txim ntawm tyrosinase los ntawm ib tug series ntawm complex biochemical tshuaj. Nws yog kis los ntawm basal txheej mus rau txheej txheej ntawm lub epidermis los ntawm sab hauv tawm los ntawm synapses. Xim daim tawv nqaij.

Tyrosinase muaj tyrosine hydroxylase kev ua haujlwm (catalyzing tyrosine los tsim dopa) thiab dopa oxidase kev ua (catalyzing dopa los tsim dopaquinone). Nyob rau hauv tus txheej txheem ntawm melanin tsim, nws ua hauj lwm raws li lub ntsiab tus nqi-limiting enzyme. Nws txoj haujlwm txiav txim siab txog qhov tsim ntawm melanin.

Arbutin yog tyrosinase inhibitor uas tuaj yeem cuam tshuam tyrosinase kev ua haujlwm zoo yam tsis muaj kev cuam tshuam cov cell proliferation concentration. Nws sib tw rau kev khi ntawm dopa los ntawm nws txoj kev khi ncaj qha rau tyrosinase. site, thaiv cov synthesis ntawm dopa thiab dopaquinone, yog li cuam tshuam nrog melanocytes thiab inhibiting zus tau tej cov melanin. Nyob rau tib lub sijhawm, nws kuj muaj cov haujlwm ntawm diluting tsim melanin, ua kom lub decomposition thiab excretion ntawm melanin, txo cov tawv nqaij pigmentation, thiab tshem tawm pob thiab freckles.

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