Feem ntau ua haujlwm txog Spermidine thiab Spermidine trihydrochloridecan hauv kev tshawb fawb

Feem ntau ua haujlwm txogSpermidine thiabSpermidine trihydrochloridetuaj yeem tshawb nrhiav

Spermidine [N-(3-aminopropyl)-1,4-diaminobutane] yog ib qho saturated linear triamine feem ntau muab faib ua nruab nrab hauv kev sib txuas ntawm spermine. Nws muaj cov mis mos molecular C1H19N3 thiab molar mass 145.25 g / mol thiab yog ib qho me me, dej-soluble, amphiphilic molecule nrog lub peev xwm nkag mus rau cov kab mob lom. Nws tshwm sim thoob plaws hauv ntau yam kab mob, tsis hais txog kev faib tawm taxonomic.

Spermidine tuaj yeem khi rau ntau hom molecules, ua rau lawv muaj txiaj ntsig zoo. Lawv txhawb cov txheej txheem suav nrog kev loj hlob ntawm tes, DNA stability, cell proliferation thiab apoptosis. Nws zoo nkaus li tias polyamines ua haujlwm zoo ib yam li cov khoom loj hlob thaum lub sijhawm cell faib. Qhov no yog vim li cas spermidine tseem ceeb rau kev noj qab haus huv cov ntaub so ntswg thiab kev ua haujlwm.

1.Anti-inflammatory zog ntawm Spermidine rau mob qog noj ntshav thiab mob plawv

Hauv kev tshawb fawb xyoo 2016, spermidine tau pom tias thim rov qab lub sijhawm laus thiab txhim kho cov hlab plawv hauv cov nas muaj hnub nyoog. Nyob rau theem ntawm lub cev, cov qauv plawv thiab kev ua haujlwm tau zoo dua qub rau cov nas uas muaj hnub nyoog muab spermidine. Metabolism kuj tau txhim kho nyob rau hauv cov nas vim yog kev kho dua tshiab ntawm mitochondrial qauv thiab kev ua haujlwm tom qab spermidine supplementation.

2. Spermidineua raws li anti-kev laus cov khoom xyaw

Hais txog kev ua neej nyob ntev, ntau yam kev tshawb fawb tsiaj tau pom tias noj cov spermidine ua rau kom muaj sia nyob thiab tiv thaiv daim siab fibrosis thiab hepatocellular carcinoma. Ib yam zoo li muaj tseeb ntawm cov khoom noj uas muaj polyamine. Kuj tseem muaj qee qhov pov thawj tias nws ua rau muaj zog tiv thaiv kev ntxhov siab, thiab kev poob qis hauv cov spermidine txhawb kev loj hlob ntawm cov kab mob muaj hnub nyoog.

3.Spermidine trihydrochloridetau rqhia kev paub tsis meej

Kev tshawb fawb luam tawm hauv phau ntawv xov xwm Cell Reports hauv 2021 cov ntsiab lus hais tias kev noj zaub mov spermidine txhim kho kev paub thiab kev ua haujlwm mitochondrial hauv yoov thiab nas, thiab muab qee cov ntaub ntawv rau tib neeg yav tom ntej.