Senolytics (senescent cell lysing agents) yog ib hom tshuaj tiv thaiv kev laus uas tuaj yeem tshem tawm cov hlwb senescent. Cov neeg paub zoo dua suav nrog rapamycin, quercetin ua ke nrog dasatinib, thiab lwm yam.
Ib tsab xov xwm xyoo 1966 tau qhia tias
fisetinyog ib qho ntawm cov flavonoids nrog cov tshuaj tua kab mob uas muaj zog tshaj plaws uas paub thaum lub sijhawm ntawd. Nws tuaj yeem cuam tshuam kev loj hlob ntawm cov kab mob xws li Staphylococcus aureus. Xyoo 2021, University of Minnesota thiab Mayo Clinic tau sib koom ua ke tso tawm ib qho kev tshawb fawb qhia tias senolytics txo qis kev tuag ntawm cov nas laus uas muaj kab mob beta-coronavirus. Cov tshuaj tiv thaiv kev laus no yog fisetin.
01 Fisetin yog dab tsi?
Fisetin, tseem hu ua
fisetin, yog ib hom ntawm ntuj flavonoid compound muab rho tawm los ntawm cov nroj tsuag xws li Anacardiaceae. Fisetin kuj pom muaj nyob rau hauv txiv hmab txiv ntoo thiab zaub thiab muaj antioxidant, anti-inflammatory thiab lwm yam pharmacological zog.
02 Lub luag haujlwm ntawm fisetin yog dab tsi?
Fisetin yog bioflavonoid antioxidant uas tuaj yeem pab tswj cov qib glutathione thiab mitochondrial muaj nuj nqi thaum muaj oxidative kev nyuaj siab. Nws muaj peev xwm hla cov ntshav-hlwb teeb meem, uas yuav pab tswj kev ua haujlwm neuronal.
01.Fisetintuaj yeem tshem tawm cov dawb radicals thiab txhim kho glutathione
Fisetin ncaj qha tshem tawm cov dawb radicals, txhim kho glutathione qib, thiab tuaj yeem pab tswj kev tsim cov protein ntau koom nrog hauv kev tiv thaiv lub cev los ntawm oxidative kev nyuaj siab thiab tswj hwm redox homeostasis. Qhov no yog lub tshuab uas glutathione ua tiav nws cov teebmeem antioxidant.
02.Fisetin kuj muaj cov tshuaj tiv thaiv qog.
Cov kev sim ua haujlwm tau ua pov thawj tias nws muaj cov tshuaj tiv thaiv tib neeg lub ntsws qog noj ntshav, tiv thaiv kab mob qog noj ntshav hauv tsev menyuam, tiv thaiv tib neeg cov qog nqaij hlav qog noj ntshav thiab tiv thaiv tib neeg cov kab mob qog noj ntshav. Nws lub luag haujlwm tseem ceeb yog ua kom lub cev sib txawv ntawm cov qog nqaij hlav cancer rau hauv cov hlwb ib txwm los ntawm kev hloov cov noob qog nqaij hlav cancer.
03.Fisetin kuj muaj qhov tshwj xeeb cuam tshuam rau lub hlwb kev noj qab haus huv, kev paub thiab kev nco.
Ntau qhov kev tshawb fawb txog qhov no tau ua nyob rau ntawm lub chaw muaj koob npe Salk rau Kev Tshawb Fawb Txog Kev Nyuaj Siab hauv San Diego, tsom rau nws txoj kev siv los ua "nootropic" thiab "neurotrophic factor." Raws li tau hais ua ntej, nws tuaj yeem hla cov ntshav-hlwb thaiv kab mob thiab tom qab ntawd ua rau "pruning" nyhuv, tshem tawm cov hlwb tsis zoo thiab tso cai rau cov hlwb noj qab haus huv los hloov cov laus, tsis muaj txiaj ntsig thiab muaj teeb meem. Thiab, qee cov neeg ntseeg tias nws lub peev xwm yog vim quercetin. Ob npaug ntau npaum li tus prime.
03 Cov ntsiab lus
Fisetin yog lub ntuj tsim tawm los ntawm cov nroj tsuag uas muaj ntau yam txiaj ntsig thiab yog ib tus tswv cuab ntawm pawg senolytics rau nws lub luag haujlwm hauv kev tshem tawm cov hlwb. Muaj ntau
fisetincov khoom lag luam tam sim no. Yog tias koj muaj cov tswv yim tiv thaiv kev laus, kuv ntseeg tias fisetin yog qhov kev xaiv zoo.
Yog xav paub ntxivcov ntaub ntawvtxog peb cov khoom thiab cov kev pabcuam thov hu rau peb.
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Irene@xahealthway.com
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